Invasive Ductal Carcinoma Causes - The cause is unknown , but there are some risk factors that cause a woman to be more likely to suffer from breast cancer. Some of these risk factors are:
Age
Approximately 60 % of breast cancers occur in over 60 years . The greatest risk was found in women aged over 75 years .
Had suffered from breast cancer
Women who have had cancer in situ or invasive cancer had the highest risk for breast cancer .
Once the affected breast removed , then the risk of breast cancer in a healthy increase of 0.5-1 % / year .
Family history of breast cancer
Women who are mothers , sisters or children suffering from cancer , had a 3 times greater risk of developing breast cancer .
Genetic and hormonal factors
Have found two variants of genes that appear to play a role in the occurrence of breast cancer , the BRCA1 and BRCA2 . If a woman has one of these genes , the likelihood of breast cancer is very large .
Other genes are also thought to play a role in the occurrence of breast cancer is p53 , BARD1 , BRCA3 and Noey2 .
This fact suggests that breast cancer is caused by the growth of cells that are genetically damaged .
Hormonal factors are also important because hormone triggers cell growth . High hormone levels during the reproductive period of a woman , especially if it is not interrupted by hormonal changes due to pregnancy , seems to increase the chances of growth of cells that have been genetically damaged and cause cancer .
Ever had a non- cancerous breast disease
The risk of breast cancer slightly higher in women who had suffered a non - cancerous breast disease that causes the increase of the ducts and breast tissue structure abnormalities ( atypical hyperplasia ) .
Menarche ( first menstruation ) before age 12 , menopause after age 55 years , first pregnancy after the age of 30 years or had never been pregnant .The earlier the menarche , the greater the risk of breast cancer . The risk of breast cancer is 2-4 times greater in women who experienced menarche before age 12 years. Similarly, the first pregnancy or menopause . The slower menopause and first pregnancy , the greater the risk of breast cancer
The use of birth control pills or estrogen replacement therapy
Birth control pills may slightly increase the risk of breast cancer , which depends on age , duration of usage and other factors . It is not known how long the effects of the pill will still be there after pill use is stopped .
Estrogen replacement therapy who lived for more than 5 years seems also slightly increase the risk of breast cancer and the risk increases if longer use .
Obesity after menopause
Obesity as a risk factor for breast cancer is still debated . Some studies suggest obesity as a risk factor for breast cancer, possibly because of the high levels of estrogen in obese women .
Alcohol consumption
The use of alcohol more than 1-2 cups / day can increase the risk of breast cancer.
Chemicals.
Several studies have cited the exposure of chemicals that mimic estrogen (which is contained in pesticides and other industrial products) may increase the risk of breast cancer.
DES (diethylstilbestrol)
Women who took DES to prevent miscarriage have a higher risk of breast cancer.
Irradiation
Exposure to radiation (especially radiation to the chest), in childhood can increase the risk of breast cancer.
Other risk factors
Several studies have shown that uterine cancer, ovarian and colon cancer as well as the presence of a family history of cancer can increase the risk of breast cancer.
